Randomly wondered today: could a Transformer get a cramp? Say, halfway through transformation, Optimus Prime gets a Charley Horse and goes down on his half-transformed knee? Seems like a Family Guy gag: "Ow," Prime says in that deep Peter Cullen voice, "ow. Ow."
I have never written Transformers. I probably won't.
(Though I like that almost to a person, writers who have written those characters have said how much fun they had writing them.)